Nalbuphine is a highly addictive Opiate analgesic meant to reduce pain among patients. Doctors will often prescribe this narcotic medication to manage moderate to severe pain. This potentially dangerous and lethal drug has a number of brand names, including Nubain (or Nubaine), Raltrox, Rubuphine, Kinz, Nalbin, and Manfine. Notably, the drug is no longer available under the name Nubain, but is still available in the same form under the remaining brands.

What is Nalbuphine?

Nalbuphine is a semi-synthetic Opioid analgesic, prescribed to reduce pain in patients by acting on the central nervous system. It is commonly available in two concentrations and is said to be as potent as Morphine. Currently, however, Nalbuphine is not scheduled under the Drug Enforcement Administration’s (DEA) classification.

If injected into a vein, Nalbuphine’s effects can be felt in just a few minutes. Other forms of administration (such as oral, subcutaneous, or intramuscular) can take up to 15 minutes to produce effects. Today, the substance is only available in the injectable form in the United States and in Europe. Overall, users can expect to experience pain relief for approximately 3 to 6 hours after initial use.

Currently, Nalbuphine is used clinically before, during, or after surgery, including during labor and delivery. This practice, however, has waned in current years, in favor of other treatments. Aside from pain management, Nalbuphine has been used to treat the itching side effect that patients receiving Morphine may experience.

History of Nalbuphine

Opiates, as a class of drugs, pose a high risk for addiction. Because of the dangerous nature of Opiates, some semi-synthetic Opiates were created in an attempt to curb these dangerous effects. Nalbuphine was one such semi-synthetic Opiate that was designed to have less abuse potential. Currently, Nalbuphine is the only approved drug that mixes agonist and antagonist properties in order to curb abuse.

Originally, Nalbuphine was classified as a Schedule II Controlled Substance by the DEA in1971. After a petition from the drug manufacturer, the substance was removed from the list in 1976. It is the only substance of its kind to remain free of government classification.

Side Effects of Nalbuphine

Along with the pain relieving result, Nalbuphine can cause the following side effects:

• Sedation;
• Respiratory depression;
• Nervousness;
• Restlessness or insomnia;
• Euphoria;
• Confusion;
• Hallucinations;
• Sweating;
• Nausea;
• Vomiting;
• Dry mouth;
• Vertigo;
• Headache;
• Dizziness;
• Asthma;
• Hypertension;
• Cramping;
• Taste of bitterness;
• Itching or burning skin;
• Irregular heart beat;
• Flushing or warmth;
• Increased urination;
• Blurred vision; or
• Difficulty with speech.

Studies have shown that sedation is the most common side effect, with approximately 36% of patients experiencing the symptom. There are additional severe risks when using any Opiate, which include addiction and even death. When used under the supervision of a physician, you will be made aware of all the risks and benefits. Unfortunately, when Nalbuphine is used illicitly, it is more likely to cause these negative side effects, including death and addiction.

Addictive Nature of Nalbuphine

Though Nalbuphine, as a semi-synthetic Opiate, was designed to decrease abuse potential, studies show that the substance is still highly addictive. The pain relief, along with the associated sense of euphoria and sedation can cause both physiological and psychological dependence.

An additional risk when using Nalbuphine is withdrawal. When used for both short-term and long-term periods, this substance can cause serious and even deadly withdrawal symptoms. These symptoms can include, but are not limited to:

• Cramping
• Nausea;
• Vomiting;
• Anxiety;
• Restlessness or insomnia;
• Fever;
• Crying or tearing;
• Excess mucus or runny nose;
• Convulsions, spasms, or tremors;
• Anxiety;
• Diarrhea;
• Goose bumps;
• Clammy skin;
• Shaking;
• Irritability; or
• Muscle aches and pains.

These undesirable effects can often be worse for those who suffer from Nalbuphine addiction, as they tend to take increased dosages for longer periods of time. This is caused by a tolerance to the drug, where increasingly large amounts of the substance are necessary to achieve the same effects. Withdrawal symptoms can begin in as little as 6 to 12 hours, making the addictive effect stronger. Often, addicts will inject more Nalbuphine when they experience these effects, in an effort to reduce the withdrawal symptoms. Unfortunately, this tends to create a vicious cycle of abuse.

Recently, a study has suggested that bodybuilders are increasingly becoming addicted to Nalbuphine. A new trend shows that anabolic steroid users frequently abuse Nalbuphine in an effort to reduce pain associated with steroids and bodybuilding. Among the subjects studied, many of them experienced negative physical or mental effects linked to Nalbuphine use.

Drug Interactions

Like many other drugs, including other Opiates, Nalbuphine should not be taken concurrently with any other drugs unless cleared by a physician. Harmful interactions can occur when taking Nalbuphine and other substances.

Addicts are at an increased risk for a lethal interaction because they do not take the medication under doctor supervision. Additionally, addicts tend to take larger doses of the substance because of their increased tolerance to the drug.

Of particular importance to addicts is Nalbuphine’s potential interaction with alcohol and Methadone. When taken with alcohol (or other depressants), Nalbuphine can produce:

• Increased drowsiness or dizziness;
• Coma;
• Slowed or difficulty breathing;
• Fainting and unresponsiveness; and even
• Death.

If Nalbuphine is use concurrently with Methadone, it may decrease the drug’s effectiveness, thus leading to potential use or abuse of Methamphetamines.

Users should also avoid mixing Nalbuphine with a number of other drugs, including those used to treat conditions such as:
• Asthma;
• High blood pressure;
• Thyroid, Liver, or Kidney disorders;
• Seizures; or
• Mental health issues.

Medications taken for any of these conditions can cause a serious or life-threatening interaction. Thus, those who are taking the substance illicitly are at an increased risk for death caused by drug interaction. Furthermore, when Nalbuphine is mixed with other drugs or illicit substances, such as Heroin, a fatal overdose is more likely to occur.

Signs and Symptoms of Nalbuphine Addiction

If you suspect that a loved one is suffering from an addiction to Nalbuphine, you may notice any of the following signs and symptoms:

• Injection instruments;
• Redness, rash, or swelling at potential injection sites;
• Any of the above-listed side-effects;
• Any of the above-listed withdrawal symptoms;
• Inability to function without the drug; or
• Drug seeking behaviors.

As with addiction to any substance, the user may experience denial or withdrawal from society, making it difficult to ascertain the true nature of his or her addiction. If you believe that your loved one may be experiencing an addiction to Nalbuphine, don’t be afraid to reach out for help.

The experienced professionals at iAddiction are here to help you start your journey to recovery. We will connect you with treatment facilities that are dedicated to guiding you through your battle against Nalbuphine. A happy, healthy, and drug free life is only one call away with our dedicated 24/7 hotline. Don’t wait another day to save yourself or a loved one from the dangers of addiction and substance abuse, call now.